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WorkspaceChat, experiments, split panes, and artifacts.Library filesUpload and reuse PDFs, CSVs, docs, and datasets.BriefsCited, scannable research documents.PresentationsTemplated, cited stakeholder decks.DashboardsInteractive, filterable analytics views.

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Documentation

Briefs

A brief turns a session into a cited, scannable research document — structured sections with every claim traceable to its source.

Open a session
Research brief
6 sources · 2 figures

GLP-1 agonists in neuroinflammation

Summary
Three independent lines of evidence support a microglial-modulating effect; human CNS readouts remain preliminary.
Key findings
  • Preclinical models converge on reduced microglial activation across two GLP-1 RAs.
  • Two early-phase trials show CSF biomarker shifts; powered for safety, not efficacy.
  • No late-phase neurodegeneration trial has reported a primary cognitive endpoint yet.
Methods

Systematic search across PubMed and ClinicalTrials.gov (2019–2026); 41 records screened, 11 met inclusion. Risk of bias assessed with RoB 2; effects summarized narratively given model heterogeneity.

Fig 1 · Microglial activation across modelsdrawn_from_data
Limitations

Human CNS readouts are limited to early-phase, safety-powered trials; no late-phase cognitive endpoint has reported yet.

Citedpubmed:36258591trial:NCT05015842chembl:CHEMBL414804

What a brief is for

Reach for a brief when you need the written record — the thesis, the evidence, and the caveats in one cited document.
Structured sections
Question, summary, key findings, evidence, limitations, open questions.
Traceable evidence
Each claim links back to the source record — PubMed, a trial, a DOI, a dataset.
Scannable takeaway
A lead takeaway up top so a reader gets the point in seconds.

Create & refine

You decide when the session is ready — the agent never writes a brief on its own. Drafts are starting points; iterate without losing prior versions.
Add brief
Click the chip under any assistant turn; add a focus or leave it blank.
Refine
A focused prompt scoped to the brief — change audience, expand a section, revisit a figure.
Regenerate
Rebuild from the full session when the first draft missed the mark.

Fix facts upstream, not in the brief

A brief is a render of the session. If a citation or chart is wrong, correct the underlying chat turn or analysis run, then Regenerate — don’t hand-edit the output.

Chart honesty

Every figure states where its data came from — the reason a brief is trustworthy on first read.
drawn_from_data
Plotted from a real session file or analysis output.
parametric
Computed from a named equation; points are model output.
simulated_illustration
An explicitly-requested illustrative shape, labeled as such.
deferred_no_data
Not enough data — Cortexa defers instead of fabricating.

Share

A brief is a first-class artifact with its own URL — private until you share it.
ShareToken linkSave as PDFRead-only · revocableEvery chart carries its chart_decision provenance.
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The agent for research teams. 2.2K+ verified tools across every research discipline, every claim cited.

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